Sperm plasma membrane

Ciliary and Flagellar Membranes pp Cite as. In this chapter the dynamics of molecular motions in the mammalian sperm plasma membrane will be discussed. Specifically, we will consider the nature of the known or potential forces which control these molecular motions. We will only discuss macromolecules that have been identified as having some physiological role and have been characterized on intact cells using biophysical techniques to gain insight into the organization of the sperm plasma membrane.
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Dynamics of the mammalian sperm plasma membrane in the process of fertilization.

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Dynamics of the mammalian sperm plasma membrane in the process of fertilization.

In keeping with all somatic cells, mammalian spermatozoa are surrounded by a limiting plasma membrane PM containing lipids, proteins, glycolipids and glycoproteins arranged in a classic bilayer structure. Spermatozoa are also highly polarised cells and their PM is compartmentalised into different regions acrosome, equatorial segment, postacrosome, midpiece and principal piece that reflect compositional and functional heterogeneity. Unlike somatic cells, however, spermatozoa are exposed to widely different environments during their lifetime, ranging from the unique milieu within the seminiferous tubules to that in the epididymis, seminal plasma, uterus, oviduct, cumulous oophorus, and eventually the perivitilline space. The PM has to be sufficiently stable physiologically to withstand these varying conditions, while at the same time sensitive enough to detect specific signals from different fluids and to react accordingly. Since spermatozoa acquire their motility and fertilizing capacity during passage through the epididymal duct, much interest has centred on the nature of the PM during their transition from an infertile to a fertile state. This information is important not only from the standpoint of elucidating the biogenesis of the molecules involved in fertilization itself, but also for understanding the aetiology of infertility in man.
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The Sperm Plasma Membrane A Little More Than Mosaic, a Little Less Than Fluid

Skip to search form Skip to main content. Dynamics of the mammalian sperm plasma membrane in the process of fertilization. In mammals complex changes in the plasma membrane of the sperm cell are involved in this process. Sperm cells have unusual membranes compared to those of somatic cells.
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