Pagets disease anus

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Extramammary Perianal Paget's Disease

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Extramammary Perianal Paget's Disease

Perianal EMPD is often reported as the involvement of perianal skin, but involvement of anal mucosa is very rare. Based on pathogenesis and association with either synchronous or metachronous malignancy, EMPD can be divided into primary and secondary types. While EMPD has been recognized for many years, very few cases are reported, thus it is considered a rare disease. The most commonly affected demography comprises females and Caucasians between ages 50 and 80 [ 3 ].
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Perianal Paget's Disease: A Case Report and Literature Review

A year-old man was referred to us because of anal bleeding. Digital rectal examination revealed a 1. Pruritis was lacking and there were no erythematous lesions or any skin lesion in the perianal region.
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Perianal Paget's disease is a rare condition characterized by an intraepidermal growth of neoplastic cells with apocrine glandular differentiation Paget's cells , often associated with an underlying malignancy. Fewer than cases have been reported in the literature over the past 20 years. Here we discuss the clinical case of a young woman who was referred to our institution for this rare disorder and briefly review the literature.
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